A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Halfway as a result of his occupation, Cees Dekker reinvented himself. Just after many years of hardcore physics, he shifted his focus to ‘nanobiology’ in the transform on the millennium. A term he coined himself, being a matter of simple fact.
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‘It absolutely was basically a make a difference of picking up a book on mobile biology and starting to study. I'd come from a globe of extremely-substantial vacuums, cryostats and quantum phenomena, and now I was working at place temperature with molecular biology kits.
Non-equilibrium folding of particular person DNA molecules recaptured as many as a thousand periods in a very stable condition nanopore
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Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en satisfied 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
Several relevant developments adopted, the place our team proven diverse transistor variants for instance one-electron transistors at place temperature and intramolecular nanotube junctions that acted as rectifying ceesdekker.net diodes, and coupled many transistors into smaller evidence-of-theory electronic circuits.
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in purple, as well as a 3D rendering of your motion with the DNA rod is displayed.
Imagine if, as an alternative to utilizing common best-down silicon electronics, transistors could be designed from the bottom up working with single organic and natural molecules because the switching features? This idea, which turned the basis of currently’s field of molecular electronics, initially emerged within the seventies.
Resolving the phase measurement in condensin-driven DNA loop extrusion identifies ATP binding since the phase-creating method
An integrated microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
1999, first measurement on the wavefunction of single molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof for a new Luttinger description of interacting electrons in nanotubes
2005, discovery of the mechanism of DNA uncoiling by topoisomerase enzymes; discovery of extensive-assortment conformational variations in Mre11/DNA maintenance complexes; and initially force measurements on the DNA molecule inside of a nanopore
Eventually, I'll briefly sketch many of our ideas to discover the creating of synthetic cells, exclusively our initially techniques to determine artificial mobile division.